{"id":6908,"date":"2025-04-08T17:10:30","date_gmt":"2025-04-08T17:10:30","guid":{"rendered":"https:\/\/beonemedicines.ca\/?page_id=6908"},"modified":"2026-01-09T14:50:54","modified_gmt":"2026-01-09T14:50:54","slug":"hematology","status":"publish","type":"page","link":"https:\/\/beonemedicines.ca\/en\/science\/research-and-development\/hematology\/","title":{"rendered":"Hematology"},"content":{"rendered":"<!-- Hero \/ Interior no image -->\r\n<section class=\"hero-interior-noimg-sec bg-primary-cerulean overflow-x-clip \">\r\n    <div class=\"card-offset-watermark watermark-rightbotttom\">\r\n        <img decoding=\"async\" src=\"https:\/\/beonemedicines.ca\/en\/wp-content\/themes\/beigene20\/assets\/img\/cutoutStar-icon.svg\" alt=\"Watermark\">\r\n    <\/div>\r\n    <div class=\"container\">\r\n        <div class=\"sec-header\">\r\n            <div class=\"sec-head\">\r\n                \r\n                <h1 class=\"anim fadeInUp\">Targeting Blood Cancers <\/h1>\r\n            <\/div>\r\n            <div class=\"sec-body\">\r\n                                                <div class=\"anim fadeInUp\">\r\n                    <p>Blood cancer is a key focus area for BeOne Medicines, particularly B-cell malignancies.<\/p>\n                <\/div>\r\n                            <\/div>\r\n                    <\/div>\r\n    <\/div>\r\n<\/section>\r\n<!-- Hero \/ Interior no image -->\r\n\r\n\n\n<!-- Copy block -->\r\n<section class=\"nav-tertiary-sec copy-block  bg-white\" >\r\n    <div class=\"container\">\r\n        <div class=\"row\">\r\n            \r\n            <div class=\"col-md-8 col-lg-9\">\r\n                \r\n                <div class=\"main-container tab-container\">                    \r\n                                                <section class=\"section anim fadeInUp \">\r\n                            <!-- <section class=\"section anim fadeInUp \" > -->\r\n                                <div class=\"sec-header\">\r\n                                    <div class=\"sec-head\">\r\n                                                                                                                    <\/div>\r\n                                    <div class=\"sec-body\">\r\n                                                                                    \r\n                                            <div><p>Blood cancers are the fifth most common type of cancer in the world, and around 1.3 million new cases of blood cancer were diagnosed globally in 2020.<sup>1<\/sup> Blood cancer typically starts in the bone marrow or lymphatic system when blood cells grow out of control.<sup>2<\/sup><\/p>\n<p>B cells are white blood cells that help protect you from infections by making antibodies.<sup>3<\/sup> In B-cell malignancies, the body produces too many abnormal B cells. These abnormal cells, or cancerous cells, are not as effective at fighting infections and can spread to other parts of the body.<sup>4<\/sup><\/p>\n<\/div>\r\n                                                                            <\/div>\r\n                                    \r\n                                                                             <!-- <style>\r\n                                            .after-buttons {\r\n                                                display: flex; gap: 30px;\r\n                                             }\r\n\r\n                                            .after-buttons a {\r\n                                                flex: ;\r\n                                            }\r\n                                         <\/style> -->\r\n                                                                             <style>\r\n                                            .after-buttons {\r\n                                                display: flex; gap: 30px; flex-wrap: wrap;\r\n                                            }\r\n\r\n                                            .after-buttons a {\r\n                                                flex: 0 1 auto;\r\n                                            }\r\n\r\n                                            .after-buttons.multiple > div {\r\n                                                flex: 0 1 calc(50% - 30px);\r\n                                            }\r\n                                        <\/style>\r\n                                     \r\n                                    \r\n                                    <div class=\"after-buttons \">\r\n                                                                            <\/div>\r\n                                <\/div>\t\r\n                            <\/section>\r\n                                                <section class=\"section anim fadeInUp \">\r\n                            <!-- <section class=\"section anim fadeInUp \" > -->\r\n                                <div class=\"sec-header\">\r\n                                    <div class=\"sec-head\">\r\n                                                                                                                            <h2>New Approaches to Treatment<\/h2>\r\n                                                                            <\/div>\r\n                                    <div class=\"sec-body\">\r\n                                                                                    \r\n                                            <div><p>There are many ways to treat blood cancer, and new options are being studied all the time. Treatments may depend on the type of blood cancer, the aggressiveness of the disease, the overall health of the patient, and many more factors. These may include surgery, chemotherapy, radiation, targeted therapy, immunotherapy, a stem cell transplant or a combination of these approaches.<sup>5<\/sup><\/p>\n<p>Today, BeOne is working to develop potential first-in-class and best-in-class therapies to address B-cell malignancies, including chronic lymphocytic leukemia \/ small lymphocytic lymphoma (CLL\/SLL). Our research areas include:<\/p>\n<ul>\n<li><strong>Targeted therapies<\/strong>, which can target specific proteins within B-cell malignancies to stop cancer growth. This includes:<\/li>\n<li style=\"list-style-type: none;\" class=\"nested-list\">\n<ul>\n<li>The cornerstone of our hematology franchise \u2013 our <em>Bruton\u2019s tyrosine kinase (BTK) inhibitor<\/em>, which can treat B-cell malignancies by shutting down (or inhibiting) proteins within cancerous B cells.<\/li>\n<li>Our late-stage B-cell lymphoma 2 (BCL2) inhibitor, which is part of a group of drugs called BH3 mimetics, which mimic natural cell death signals.<\/li>\n<\/ul>\n<\/li>\n<li><strong>Protein degraders <\/strong>from our Chimeric Degradation Activation Compound (CDAC) platform<strong>, <\/strong>which use the cell\u2019s natural ability to dispose of unwanted cells like cancer cells. By harnessing this approach, therapies like protein degraders target cancer cell proteins to signal for them to be destroyed.<\/li>\n<\/ul>\n<\/div>\r\n                                                                            <\/div>\r\n                                    \r\n                                        <div class=\"sec-buttons\">\r\n                                            <a href=\"\/en\/science\/research-and-development\/\" target=\"_self\" class=\"btn-default btn-primary btn-crosslinks \">\r\n                                                <span>Learn more about our research and development approach<\/span>\r\n                                            <\/a>\r\n\r\n                                            \r\n                                        <\/div>\r\n                                    \r\n                                                                             <!-- <style>\r\n                                            .after-buttons {\r\n                                                display: flex; 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gap: 30px;\r\n                                             }\r\n\r\n                                            .after-buttons a {\r\n                                                flex: ;\r\n                                            }\r\n                                         <\/style> -->\r\n                                                                             <style>\r\n                                            .after-buttons {\r\n                                                display: flex; gap: 30px; flex-wrap: wrap;\r\n                                            }\r\n\r\n                                            .after-buttons a {\r\n                                                flex: 0 1 auto;\r\n                                            }\r\n\r\n                                            .after-buttons.multiple > div {\r\n                                                flex: 0 1 calc(50% - 30px);\r\n                                            }\r\n                                        <\/style>\r\n                                     \r\n                                    \r\n                                    <div class=\"after-buttons \">\r\n                                                                            <\/div>\r\n                                <\/div>\t\r\n                            <\/section>\r\n                                    <\/div>\r\n                \r\n            <\/div>\r\n            <div class=\"col-md-4 col-lg-3\">\r\n                \r\n            <\/div> \r\n        <\/div>\r\n    <\/div>\r\n<\/section>\r\n<!-- Copy block -->\r\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":7110,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-6908","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hematology - BeOne Medicines EN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beonemedicines.ca\/en\/science\/research-and-development\/hematology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hematology - BeOne Medicines EN\" \/>\n<meta property=\"og:url\" content=\"https:\/\/beonemedicines.ca\/en\/science\/research-and-development\/hematology\/\" \/>\n<meta property=\"og:site_name\" content=\"BeOne Medicines EN\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-09T14:50:54+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/beonemedicines.ca\\\/en\\\/science\\\/research-and-development\\\/hematology\\\/\",\"url\":\"https:\\\/\\\/beonemedicines.ca\\\/en\\\/science\\\/research-and-development\\\/hematology\\\/\",\"name\":\"Hematology - BeOne Medicines EN\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/beonemedicines.ca\\\/en\\\/#website\"},\"datePublished\":\"2025-04-08T17:10:30+00:00\",\"dateModified\":\"2026-01-09T14:50:54+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/beonemedicines.ca\\\/en\\\/science\\\/research-and-development\\\/hematology\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/beonemedicines.ca\\\/en\\\/science\\\/research-and-development\\\/hematology\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/beonemedicines.ca\\\/en\\\/science\\\/research-and-development\\\/hematology\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/beonemedicines.ca\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Science\",\"item\":\"https:\\\/\\\/beonemedicines.ca\\\/en\\\/science\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Research &amp; 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